NYTimes editorial on OA to drug trial data
Hiding the Data on Drug Trials, New York Times, June 1, 2005 (free registration required). An unsigned editorial. Excerpt: ‘Any Americans gullible enough to believe that the drug industry can be trusted to report fully on what clinical trials it is sponsoring or what results were found must be sorely disappointed by recent developments. A government survey determined that three of the largest drug companies have effectively reneged on their pledges to list trials in a federal database. A report in yesterday’s Times by Alex Berenson reveals that this intransigence also extends to a voluntary industry database….A public listing of trials is important to prevent drug makers from hiding results that reflect badly on their drugs while publishing only results that make their drugs look good. By law, the companies are supposed to register important trials with a government Web site. Most manufacturers are complying, but the three big obfuscators - Merck, GlaxoSmithKline and Pfizer - are often getting around the requirement by not naming the drugs they are testing, instead using phrases like “an investigational drug.” Merck was the worst offender, failing to provide a drug’s name some 90 percent of the time. Glaxo withheld a name 53 percent of the time, and Pfizer 36 percent of the time….A coalition of medical editors has just stiffened its announcement that leading journals will soon refuse to publish the results of any clinical trial that has not complied with tough international standards for transparency. That should apply useful pressure to recalcitrant companies. But the best hammer would be federal legislation to compel all companies to provide critical information when a trial is begun and full results when a trial is completed, with stiff penalties for noncompliance.’
